Hepatitis C virus (HCV) infection and re-infection among HCV- and HIV/HCV-infected injection drug users

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Hepatitis C virus (HCV) infection and re-infection among HCV- and HIV/HCV-infected injection drug users

Methods We identified a cohort of IDUs receiving care at the Pender Community Health Centre on Vancouver’s Downtown East Side. Potential subjects were identified as either never having been infected with HCV (noninfected arm), having spontaneously cleared the virus (spontaneous arm), or having achieved a sustained virologic response on antiviral treatment (SVR arm). A questionnaire to identify ...

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Factors associated with interest in initiating treatment for hepatitis C Virus (HCV) infection among young HCV-infected injection drug users.

OBJECTIVE We sought to identify factors associated with interest in receiving therapy for hepatitis C virus (HCV) infection among HCV-infected injection drug users (IDUs) in 3 United States cities. METHODS IDUs aged 18-35 years who were HCV-infected and seronegative for human immunodeficiency virus underwent surveys on behaviors, experience, and interest in treatment for HCV infection and rea...

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MBL2 and Hepatitis C Virus Infection among Injection Drug Users

BACKGROUND Genetic variations in MBL2 that reduce circulating levels and alter functional properties of the mannose binding lectin (MBL) have been associated with many autoimmune and infectious diseases. We examined whether MBL2 variants influence the outcome of hepatitis C virus (HCV) infection. METHODS Participants were enrolled in the Urban Health Study of San Francisco Bay area injection ...

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Hepatitis C virus (HCV) core antigen assay to detect ongoing HCV infection in thai injection drug users.

We evaluated a quantitative enzyme immunoassay (trak-C) for hepatitis C virus core antigen (HCV core Ag) by testing serum specimens from 820 injection drug users in Thailand with anti-HCV antibodies. The HCV genotypes in this population include genotypes 3 and 6, which have not been extensively tested with this assay. Among these specimens, 629 (76.7%) yielded positive results, with HCV core Ag...

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CD81 and Hepatitis C Virus (HCV) Infection

Hepatitis C Virus (HCV) infection is a global public health problem affecting over 160 million individuals worldwide. Its symptoms include chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. HCV is an enveloped RNA virus mainly targeting liver cells and for which the initiation of infection occurs through a complex multistep process involving a series of specific cellular entry fac...

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ژورنال

عنوان ژورنال: Journal of the International AIDS Society

سال: 2010

ISSN: 1758-2652,1758-2652

DOI: 10.1186/1758-2652-13-s4-p199